There is a very strong link between acne and diet. The prevalence of acne, a distressing skin condition, is very high. On average it is as high as 79 to 85% in adolescents and 40 to 54% in people aged 25 and older. 12% of women and 3% men in their middle age have acne.

The true cause of acne is unknown. The fact that there is a lower incidence of acne in non-Western countries raises the possibility of a link between acne and low carbohydrate intake. The theory is that high carbohydrate intake causes raised Insulin level (Hyperinsulinemia). Insulinaemia is an important part of acne in general because it affects androgenic hormones and growth factor.

Dr. Robin. N. Smith and colleagues, in a study, used randomised low glycemic load diet and a control diet that was rich in carbohydrates. The low glycemic load diet had 45% energy from low glycemic Index carbohydrate and 25% from protein. Included in the study were 45 male aged 15 to 24 years. The study was carried out at the RMIT University in Melbourne, Australia. This is the first randomised controlled trial to examine the influence the effects of glycemic load